Prenatal exposure to exogenous progesterone adversely affects fetal development in Albino rats
نویسندگان
چکیده
Abstract Background The current study was carried out to investigate the effects of exogenous progesterone on fetal development in rats. Results Placental weights did not vary control and treated groups. Fetal were significantly reduced low- high-dose CVL both treatment groups compared group. In fetuses that received maternal with progesterone, several parts skeleton showed incomplete ossification. Alkaline phosphatase decreased bones born progesterone-treated dams. testes ovaries dams low high doses degenerative seminiferous tubules failed sex cord into primordial follicles, respectively. Conclusions administration during pregnancy adversely influences growth, skeletal construction, organ development.
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ژورنال
عنوان ژورنال: The Journal of Basic and Applied Zoology
سال: 2021
ISSN: ['2090-990X', '2090-9896']
DOI: https://doi.org/10.1186/s41936-021-00212-3