Prenatal carcinogenesis. An Appraisal

The relationship between aging and carcinogenesis: a critical appraisal.

The incidence of cancer increases with age in humans and in laboratory animals alike. There are different patterns of age-related distribution of tumors in different organs and tissues. Aging may increase or decrease the susceptibility of various tissues to initiation of carcinogenesis and usually facilitates promotion and progression of carcinogenesis. Aging may predispose to cancer by several...

Prenatal susceptibility to carcinogenesis by xenobiotic substances including vinyl chloride.

The carcinogenicity of vinyl chloride for experimental animals when administered transplacentally is reviewed in comparison with known transplacental carcinogens, including those that, like vinyl chloride, are dependent on enzyme-mediated metabolic conversion to a reactive intermediate in maternal or fetal tissues. Vinyl chloride is converted by mixed-function oxidases to the reactive metabolit...

Sustainable solid waste management: An appraisal of institutional limitations

This study investigates the underlying factors elucidating why solid waste management in Eldoret Town, Kenya, has up to now remained inadequate notwithstanding the existing legal framework that mandates the County Government of Uasin Gishu to ensure that all residents have access to a clean and healthy environment. The study adopted a descriptive research design. While, primary data were collec...

An Appraisal of Competency.

Ginkgo biloba--an appraisal.

Ginkgo biloba has been used in traditional Chinese medicine for about 5000 years. A standardized preparation, EGb 761 has been recently prepared. The pharmacologically active constituents, flavonol glycosides and the terpene lactones are standardized. The terpene lactones comprise of ginkgolides A, B, C and bilobalides. The extract scavenges excess free radicals and pretreatment with EGb 761 re...