Prenatal Androgen Exposure, Preoptic Area and Reproductive Functions in the Female Rat

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Prenatal androgen exposure, preoptic area and reproductive functions in the female rat.

Pregnant rats were injected with 4 mg of testosterone propionate (TP) from days 15 to 22 of pregnancy or a single dose of 4 mg TP on day 17 or 21 of pregnancy. Female offspring treated with TP or the vehicle prenatally were sacrificed at 90 days of age. The volume of the cluster of intensely stained neurons in the medial preoptic area, the "sexually dimorphic nucleus of the preoptic area" (SDN-...

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Estradiol-sensitive projection neurons in the female rat preoptic area

Electrical stimulation of the preoptic area (POA) interrupts the lordosis reflex, a combined contraction of back muscles, in response to male mounts and the major receptive component of sexual behavior in female rat in estrus, without interfering with the proceptive component of this behavior or solicitation. Axon-sparing POA lesions with an excitotoxin, on the other hand, enhance lordosis and ...

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Consequences of prenatal androgen exposure for the reproductive performance of female pheasants (Phasianus colchicus).

Maternal hormones in vertebrate eggs can mediate important forms of maternal effects. However, the function of hormone transfer to the eggs is still debated, especially because long-term fitness consequences have been little studied. We investigated the effect of prenatal exposure to physiologically elevated yolk testosterone (T) levels on reproduction of female pheasants (Phasianus colchicus) ...

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Expression of Luteinizing Hormone (LH) Receptor Gene in the Ovary of a Prenatally-Androgenized Rat Model of Polycystic Ovary Syndrome Following Androgen Exposure in the Prenatal Period

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ژورنال

عنوان ژورنال: Juntendo Medical Journal

سال: 1987

ISSN: 0022-6769,2188-2134

DOI: 10.14789/pjmj.33.406