Preliminary identification of potential phytochemical components as antiviral agents against Dengue Virus 2: An <i>in silico</i> study

Dengue fever is an infectious disease of the dengue virus. It becomes a severe problem, particularly prevalent in tropics and subtropical countries. The can make life-threatening illness at any age people. Still, there no definite treatment regimen for infection. Nature vast reservoir precious phytochemical substances that be explored to develop new phytotherapeutics treatment. Using natural resources either directly as pharmaceuticals or structural base chemical synthesis optimize development antiviral agents against dengue. In this paper, we have tried determine therapeutic potentialities some products through <i>in silico</i> study. We had studied inhibitory pattern five components (baicalein, fisetin, fucoidan, hyperoside, β-carboline) envelope protein virus serotype-2. Among components, baicalein β-carboline were potential phytochemicals inhibit early step viral infection after binding with protein. Other did not show satisfactory results. This result will helpful medicines from resources.