preDQ – a software tool for peptide binding prediction to HLA‐DQ2 and HLA‐DQ8

preDQ is a software tool for peptide binding prediction to HLA-DQ2 and HLA-DQ8 proteins specially designed developed the European Food Safety Authority. The able identify peptides and/or predict their affinities. used assess risk of novel cause celiac disease. Predictions made by are based on five models assessment reported outputs. using datasets known non-binding proteins. compiled from literature curated. Ligand-based structure-based methods applied in development computational models. validated internal cross-validation procedures external test sets. Only best performing selected included preDQ. comprehensive, user friendly reliable assessing affinity capacity origin