Predictors of ovarian response: progress towards individualized treatment in ovulation induction and ovarian stimulation

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Predictors of ovarian response: progress towards individualized treatment in ovulation induction and ovarian stimulation.

Ovarian stimulation is applied in the clinic to restore mono-ovulatory cycles in anovulatory women (ovulation induction) or to induce the development of multiple dominant follicles for assisted reproduction. Ovarian response is the endocrine and follicular reaction of the ovaries to stimulation. Achieving an appropriate ovarian response to anti-estrogens or exogenous gonadotrophins is central t...

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I-24: Individualized Controlled Ovarian Stimulation (iCOS)

Background: With the recent development of recombinant gonadotropins (FSH and LH), it has become possible to further adjust the stimulation protocol according to the expected needs of the patient. In this respect, the possible beneficial role of exogenous LH activity supplementation for stimulated ART cycles has received increasing attention. According to the two-cell, two- gonadotropin theory,...

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Individualized controlled ovarian stimulation in expected poor-responders: an update

Controlled ovarian stimulation with subsequent multi-follicular development continues to be a keystone in ART. Evidence supports an individualized approach to ovarian stimulation, usually involving combinations of ovarian reserve tests, body mass index and age to tailor the exogenous gonadotropin dose, and potentially adjuvant treatment aiming for high safety and a shortening of time to live bi...

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Ovulation induction and ovarian cancer: is there a link?

Ovarian cancer accounts for approximately 4% of all cancers occurring in women and ranks the fourth most frequent cause of cancer-related death in women. Despite aggressive treatment modalities the 5 year survival rate remains less than 30%'. Almost 2.5% of all live births/ year result from assisted reproductive techniques (ARD2. Concern has been expressed that exposure to fertility drugs (FD) ...

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Ovarian epithelial dysplasia after ovulation induction: time and dose effects.

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ژورنال

عنوان ژورنال: Human Reproduction Update

سال: 2007

ISSN: 1460-2369,1355-4786

DOI: 10.1093/humupd/dmm034