Predictors for partial suppression of spermatogenesis of hormonal male contraception
نویسندگان
چکیده
منابع مشابه
Predictors for partial suppression of spermatogenesis of hormonal male contraception.
AIM To analyze factors influencing the efficacy of hormonal suppression of spermatogenesis for male contraception. METHODS A nested case-control study was conducted, involving 43 subjects, who did not achieve azoospermia or severe oligozoospermia when given monthly injections of 500 mg testosterone undecanoate (TU), defined as partial suppressors compared with 855 subjects who had suppressed ...
متن کاملInvestigation of hormonal male contraception in African men: suppression of spermatogenesis by oral desogestrel with depot testosterone.
BACKGROUND Suppression of spermatogenesis to azoospermia is required for effective hormonal male contraception, but the degree of suppression varies between ethnic groups. We here report the first study of hormonal suppression of spermatogenesis in two African centres using a regimen of oral progestogen with depot testosterone. METHODS A total of 31 healthy men (21 black) were recruited in Cape...
متن کاملMale hormonal contraception: suppression of spermatogenesis by injectable testosterone undecanoate alone or with levonorgestrel implants in chinese men.
Monthly injections of testosterone undecanoate (TU) act as a male contraceptive by reversibly suppressing spermatogenesis to azoospermia or severe oligoazoospermia in 95% of Chinese men. In 5% of Chinese men, however, monthly TU administered alone fails to suppress spermatogenesis into contraceptive ranges, or sperm "rebound," leading to occurrences of pregnancy during treatment. Since combinat...
متن کاملAdvances in male hormonal contraception
Contraception is a basic human right for its role on health, quality of life and wellbeing of the woman and of the society as a whole. Since the introduction of female hormonal contraception the responsibility of family planning has always been with women. Currently there are only a few contraceptive methods available for men, but recently, men have become more interested in supporting their pa...
متن کاملDeterminants of the rate and extent of spermatogenic suppression during hormonal male contraception: an integrated analysis.
CONTEXT Male hormonal contraceptive methods require effective suppression of sperm output. OBJECTIVE The objective of the study was to define the covariables that influence the rate and extent of suppression of spermatogenesis to a level shown in previous World Health Organization-sponsored studies to be sufficient for contraceptive purposes (< or =1 million/ml). DESIGN This was an integrat...
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ژورنال
عنوان ژورنال: Asian Journal of Andrology
سال: 2008
ISSN: 1008-682X,1745-7262
DOI: 10.1111/j.1745-7262.2008.00432.x