Predicting the Particle Deposition in Airways for Pulmonary DDS
نویسندگان
چکیده
منابع مشابه
Modeling airflow and particle transport/deposition in pulmonary airways.
A review of research papers is presented, pertinent to computer modeling of airflow as well as nano- and micron-size particle deposition in pulmonary airway replicas. The key modeling steps are outlined, including construction of suitable airway geometries, mathematical description of the air-particle transport phenomena and computer simulation of micron and nanoparticle depositions. Specifical...
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The hazard caused by inhaled particles depends on the site at which they deposit within the respiratory system. Knowledge of respiratory aerosol deposition rates and locations is necessary to (1) evaluate potential health effects and establish critical exposure limits and (2) design effective inhaled medications that target specific lung regions. Particles smaller than 10 μm in diameter can be ...
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this thesis is based upon the works of samuel beckett. one of the greatest writers of contemporary literature. here, i have tried to focus on one of the main themes in becketts works: the search for the real "me" or the real self, which is not only a problem to be solved for beckett man but also for each of us. i have tried to show becketts techniques in approaching this unattainable goal, base...
15 صفحه اولPollen deposition in intrathoracic airways.
The pathophysiological mechanisms of pollen-induced asthma have until now remained unclear, because pollen particles have generally been considered too large to penetrate into the lower respiratory tract. Such grains are therefore believed to be unable to induce an immunological response in the lower respiratory tract. There is evidence, however, that a small percentage of large particles (20-3...
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Background: As a result of dissimilarity in lung morphometry and physiological conditions, therapeutic aerosol particles deposit differently in humans of various ages and body weights. Recently, clinical findings observed low interand intrapatient reliability in dosing, suggesting that a single aerosol device and particle size distribution is ineffective. Methods: This work conducts a formal op...
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ژورنال
عنوان ژورنال: Hosokawa Powder Technology Foundation ANNUAL REPORT
سال: 2018
ISSN: 2189-4663
DOI: 10.14356/hptf.16114