Predicting Functional Effect of Human Missense Mutations Using PolyPhen‐2
نویسندگان
چکیده
منابع مشابه
Predicting functional effect of human missense mutations using PolyPhen-2.
PolyPhen-2 (Polymorphism Phenotyping v2), available as software and via a Web server, predicts the possible impact of amino acid substitutions on the stability and function of human proteins using structural and comparative evolutionary considerations. It performs functional annotation of single-nucleotide polymorphisms (SNPs), maps coding SNPs to gene transcripts, extracts protein sequence ann...
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ژورنال
عنوان ژورنال: Current Protocols in Human Genetics
سال: 2013
ISSN: 1934-8266,1934-8258
DOI: 10.1002/0471142905.hg0720s76