منابع مشابه
Exercise, cognition, and the aging brain.
We provide a brief review of the literature on exercise effects on brain and cognition. To this end, we focus on both prospective and retrospective human epidemiological studies that have examined the influence of exercise and physical activity on cognition and dementia. We then examine the relatively small set of human randomized clinical trials that have, for the most part, focused on exercis...
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Cognitive dysfunction and dementia have recently been proven to be common (and underrecognized) complications of diabetes mellitus (DM). In fact, several studies have evidenced that phenotypes associated with obesity and/or alterations on insulin homeostasis are at increased risk for developing cognitive decline and dementia, including not only vascular dementia, but also Alzheimer's disease (A...
متن کاملEpigenetic determinants of healthy and diseased brain aging and cognition.
A better understanding of normal and diseased brain aging and cognition will have a significant public health impact, given that the oldest-old persons older than 85 years of age represent the fastest-growing segment in the population in developed countries, with more than 30 million new cases of dementia predicted to occur worldwide each year by 2040. Dysregulation of gene expression and, more...
متن کاملEditorial: Perception and Cognition: Interactions in the Aging Brain
Healthy aging can lead to declines in both perceptual and cognitive functions. Many of the studies in this Topic demonstrate such age-related declines, but also identify links between them. Encouragingly, these links suggest that improving perception could benefit cognition. In addition, while compensatory cognitive strategies were mainly unsuccessful in improving perception, cognitive training...
متن کاملCortical microinfarcts and demyelination significantly affect cognition in brain aging.
BACKGROUND AND PURPOSE Microvascular lesions are common in brain aging, but their clinical impact is debated. Methodological problems such as the masking effect of concomitant pathologies may explain discrepancies among previous studies. To evaluate the cognitive consequences of such lesions, we prospectively investigated elderly individuals with various degrees of cognitive impairment but with...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 2009
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2008.12.003