Preclinical safety assessment of standardized extract of Centella asiatica (L.) urban leaves
نویسندگان
چکیده
منابع مشابه
Profiling of Centella Asiatica (l.) Urban Extract
Centella Asiatica is one of those phytochemical that has been consume for hundreds years and it is claimed that the plant possess various healing effect and antioxidant properties. For many years, a lot of commercial and medicinal researches have been focusing their resources on this plant. Hence, the profiling of this plant is vital. This study was done to investigate the behaviour of active c...
متن کاملAssessment report on Centella asiatica (L.) Urban, herba
Herbal preparation(s) The following designations are synonyms to define a highly refined and purified ethanolic (70% V/V) extract containing asiaticoside (40%) and 60% of triterpenic genins: asiatic acid (29-30%), madecassic (acid 29-30%) and madasiatic acid (about 1%). TECA (titrated extract of Centella asiatica) TTFCA (total triterpenoid fraction of Centella asiatica) TTF (total triterpenic f...
متن کاملPharmacognostic Studies on Centella Asiatica (l) Urban
The paper deals with pharmacognosy of Centella asiatica (L.) Urban, including its morphological, anatomical, chemical constituents and powder analysis. Stomata are mostly anisotricytic, isotricytic and few tetracytic. Sphaero-crystals of calcium oxalate are observed in palisade, spongy and ground parenchyma of leaf lamina, petiole and rhizome and absent in roots. Uniseriate flagellate conical h...
متن کاملProphylactic effects of asiaticoside-based standardized extract of Centella asiatica (L.) Urban leaves on experimental migraine: Involvement of 5HT1A/1B receptors.
The present study aimed at evaluation of prophylactic efficacy and possible mechanisms of asiaticoside (AS) based standardized extract of Centella asiatica (L.) Urban leaves (INDCA) in animal models of migraine. The effects of oral and intranasal (i.n.) pretreatment of INDCA (acute and 7-days subacute) were evaluated against nitroglycerine (NTG, 10 mg·kg(-1), i.p.) and bradykinin (BK, 10 μg, in...
متن کاملEffect of Centella asiatica L
In the present study the effect of Centella asiatica L. extract was studied against the genotoxic doses of ethinylestradiol on human lymphocytes culture. The different doses of C. asiatica L. extract i.e. 1.075×10 -4 , 2.125×10 -4 and 3.15×10 -4 g/ml were treated separately with 5 μM of ethinylestradiol. Similar treatments were given with 10 μM of ethinylestradiol. The treatments result in a si...
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ژورنال
عنوان ژورنال: Toxicology International
سال: 2015
ISSN: 0971-6580
DOI: 10.4103/0971-6580.172251