Prdm9 Polymorphism Unveils Mouse Evolutionary Tracks
نویسندگان
چکیده
منابع مشابه
Prdm9 Polymorphism Unveils Mouse Evolutionary Tracks
PR/SET domain containing 9 (Prdm9) mediates histone modifications such as H3K4me3 and marks hotspots of meiotic recombination. In many mammalian species, the Prdm9 gene is highly polymorphic. Prdm9 polymorphism is assumed to play two critical roles in evolution: to diversify the spectrum of meiotic recombination hotspots and to cause male hybrid sterility, leading to reproductive isolation and ...
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ژورنال
عنوان ژورنال: DNA Research
سال: 2014
ISSN: 1340-2838,1756-1663
DOI: 10.1093/dnares/dst059