Prazosin plasma concentration and blood pressure reduction.

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Prazosin plasma concentration and blood pressure reduction.

Prazosin was administered to 16 patients with essential hypertension in an initial dose of 0.5 mg, after which the blood pressure (BP), pulse, and plasma concentrations of prazosin were measured at 0, 0.5, 1, 1.5, 2, 2.5, 3, 4, 6, 8, and 24 hours. The dose of prazosin was then increased over 16 to 20 weeks, and similar sequences of measurements were obtained twice. Eleven patients completed the...

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ژورنال

عنوان ژورنال: Hypertension

سال: 1982

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.4.1.93