Practical Syntheses of Immunologically Relevant β-Glycosides of 2-Acetamido-2-deoxy-D-mannopyranose. MethylN-Acetyl-β-D-mannosaminide,N-Acetyl-β-D-mannosaminyl-(1→6)-D-galactose, and MethylN-Acetyl-β-D-mannosaminyl-(1→4)-α-D-glucopyranoside
نویسندگان
چکیده
منابع مشابه
Methyl 2-acetamido-2-deoxy-β-D-glucopyranoside dihydrate and methyl 2-formamido-2-deoxy-β-D-glucopyranoside.
Methyl 2-acetamido-2-deoxy-β-D-glucopyranoside (β-GlcNAcOCH(3)), (I), crystallizes from water as a dihydrate, C(9)H(17)NO(6)·H(2)O, containing two independent molecules [denoted (IA) and (IB)] in the asymmetric unit, whereas the crystal structure of methyl 2-formamido-2-deoxy-β-D-glucopyranoside (β-GlcNFmOCH(3)), (II), C(8)H(15)NO(6), also obtained from water, is devoid of solvent water molecul...
متن کامل2,3,4,6-Tetra-O-acetyl-2-phthalimido-β-d-glucopyranoside
In the crystal structure of the title compound, C(24)H(27)NO(11), a substituted tetra-acetyl glucopyran-oside derivative, weak inter-molecular C-H⋯O hydrogen bonds link the mol-ecules into ribbons propagated in [010]. The d configuration has been attributed on the basis of the synthesis and the β anomer has been determined from the structure.
متن کامل2,3,4,6-Tetra-O-acetyl-β-d-galactopyranosyl 2,3,4,6-tetra-O-acetyl-β-d-glucopyranosyl disulfide tetrahydrofuran solvate
The asymmetric unit of title compound, C(28)H(38)O(18)S(2)·C(4)H(8)O, comprises one disulfide-bridged sugar molecule and one solvent molecule. No significant differences in structural parameters are found between the present structure and the previously determined unsolvated form [Brito, López-Rodríguez, Bényei & Szilagyi (2006 ▶). Carbohydr. Res.341, 2967-2972]. The compounds are characterized...
متن کاملRole of N-acetyl-β-d-hexosaminidase in cholesteatoma tissue
Cholesteatoma is a destructive disease characterized by the progressive expansion of keratinizing squamous epithelium in the middle ear and mastoid, and chronic inflammatory reaction of the subepithelial connective tissue. N-Acetyl-β-d-hexosaminidase (HEX) catalyzes the release of terminal non-reducing N-acetyl-d-hexosamine residues acting on glucosides and galactosides in glycoproteins, GM2-ga...
متن کامل2,3,4,6-Tetra-O-acetyl-β-d-galactopyranosyl butyrate
The title compound, C(18)H(26)O(11), was synthesized by a condensation reaction of 2,3,4,6-tetra-O-acetyl-α-d-galactopyranosyl bromide and butyric acid. The acet-oxy-methyl and butyrate groups are located on the same side of the pyran ring, showing the β configuration for the d-glycosyl ester; the butyl group adopts an extend conformation, the C-C-C-C torsion angle being 179.1 (7)°. In the crys...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1988
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.61.1291