منابع مشابه
Repressing differentiation
ain Cheeseman, Georjana Barnes (University of California, Berkeley, CA), and colleagues have peered into a 28-protein mix and found the individual residues responsible for attaching and detaching chromosomes and microtubules. The phosphorylation of these residues by Ipl1p (an Aurora kinase) apparently allows budding yeast cells to convert monopolar chromosome spindle attachments to bipolar atta...
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The homeotic genes that determine floral organ identity in plants turn out to be regulated by trans-acting factors related to the Polycomb-group proteins that have long been known as regulators of homeotic gene expression in Drosophila.
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A myriad of coordinated signals control cellular differentiation. Reprogramming the cell's proteome drives global changes in cell morphology and function that define cell phenotype. A switch in alternative splicing of many pre-mRNAs encoding neuronal-specific proteins accompanies neuronal differentiation. Three groups recently showed that the global splicing repressor, polypyrimidine track-bind...
متن کاملA Repressing the neuron within
A myriad of coordinated signals control cellular differentiation. Reprogramming the cell’s proteome drives global changes in cell morphology and function that define cell phenotype. A switch in alternative splicing of many pre-mRNAs encoding neuronal-specific proteins accompanies neuronal differentiation. Three groups recently show that the global splicing repressor, polypyridmine track binding...
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Multiple endocrine neoplasia type 1 (MEN1) results from mutations in the tumor suppressor gene, MEN1, which encodes nuclear protein menin. Menin is important for suppressing tumorigenesis in various endocrine and certain non-endocrine tissues. Although menin suppresses MEN1 through a variety of mechanisms including regulating apoptosis and DNA repair, the role of menin in regulating cell prolif...
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ژورنال
عنوان ژورنال: Journal of the Japanese Association for Petroleum Technology
سال: 1939
ISSN: 1881-4131,0370-9868
DOI: 10.3720/japt.7.54