PP-116 The prevalence of hepatitis delta virus (HDV) and different ethnical groups in Sind, Pakistan

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Hepatitis Delta Virus: HDV-HBV Interactions

The hepatitis delta virus (HDV) is a subviral agent that utilizes the envelope proteins of the hepatitis B virus (HBV) for cell to cell propagation. In infected human hepatocytes, the HDV RNA genome can replicate and associate with multiple copies of the delta protein to assemble a ribonucleoprotein (RNP). However the RNP cannot exit the cell because of the lack of an export system. This is pro...

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Initiation of hepatitis delta virus (HDV) replication: HDV RNA encoding the large delta antigen cannot replicate.

The hepatitis delta virus (HDV) nucleocapsid consists of a genomic-length RNA of 1.7 kb and approximately equimolar amounts of the small and large forms of the hepatitis delta antigen (S-HDAg and L-HDAg, respectively). Since HDV RNA particles contain not only a genomic RNA species encoding S-HDAg but also an RNA species encoding L-HDAg, which is produced by an RNA-editing process, the question ...

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Prevalence of Hepatitis Delta Virus (HDV) Infection in Chronic Hepatitis B Patients with Unusual Clinical Pictures

BACKGROUND Probably 5% of the HBV carriers have HDV super infection. The risk of fulminant hepatitis, cirrhosis and hepatocellular carcinoma is higher in superinfection than the settings when HBV is alone. OBJECTIVES The aim of this study was to evaluate the prevalence of HDV in Iranian HBV isolates and to compare their clinical and virological pictures as well as their HDV genetic variations...

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prevalence of hepatitis delta virus (hdv) infection in chronic hepatitis b patients with unusual clinical pictures

results 12 (14.8%) patients had positive results for both hdv rna and anti-hdv. the mean alt level was higher in hdv positive patients (75.9 u/ml) than hbv-mono-infected individuals; however, the mean hbv viral load was lower in coinfected patients than hbv-mono-infected patients. phylogenetically, genotype i was the only detected genotype, and the most closely related isolates were of turkish,...

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Prevalence of hepatitis delta virus infection in various groups with HBVinfection in Tehran, Imam Khomeini Hospital (2005-2006)

    Abstract   Background: Hepatitis B virus infection is an important cause of liver morbidity and   mortality worldwide. HDV changes the natural course of HBV. The prevalence of HDV infection wasn’t determined in the various groups of HBV infection (carriers, acute hepatitis, chronic hepatitis, cirrhosis and HCC) in Iran. We aimed to research the prevalence of hepatitis D virus infection in v...

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ژورنال

عنوان ژورنال: International Journal of Infectious Diseases

سال: 2011

ISSN: 1201-9712

DOI: 10.1016/s1201-9712(11)60268-3