Potentiation of Opioid Analgesia by Psychostimulant Drugs
نویسندگان
چکیده
منابع مشابه
Psychostimulant Drugs and Neuroplasticity
Drugs of abuse induce plastic changes in the brain that seem to underlie addictive phenomena. These plastic changes can be structural (morphological) or synaptic (biochemical), and most of them take place in the mesolimbic and mesostriatal circuits. Several addiction-related changes in brain circuits (hypofrontality, sensitization, tolerance) as well as the outcome of treatment have been visual...
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Substance abuse and addiction are the most costly of all the neuropsychiatric disorders. In the last decades, much progress has been achieved in understanding the effects of the drugs of abuse in the brain. However, efficient treatments that prevent relapse have not been developed. Drug addiction is now considered a brain disease, because the abuse of drugs affects several brain functions. Neur...
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ژورنال
عنوان ژورنال: Journal of Pain and Symptom Management
سال: 1998
ISSN: 0885-3924
DOI: 10.1016/s0885-3924(98)00084-0