Potential Role of Intermittent Fasting and Fasting-Mimicking Diet in Prevention of Diabetes and Cardiovascular Disease

Introduction: Prediabetes, diabetes and cardiovascular disease (CVD) are highly prevalent diseases around the world. They cause numerous complications that result in significant morbidity mortality. Nutrition plays an important role reducing CVD risk. This study explores potential effects of fasting, fasting-mimicking diets, time-restricted eating on reduction risk factors provides initial data their benefits prevention treatment options. Method: prospective cohort involed 31 male adult participants. All them were provided with VLCD meal replacements (OPTIFAST®), instructed to practice IF 14 hours a day for 4 weeks. The parameters measured before after intervention body mass index (BMI), fasting blood sugar (FBS), total cholesterol (TC) levels. Student's T test was utilized statistical significance results. Results: average BMI 38.03 (±SD 4.69) 36.19 4.26) study, but this not statistically significant. Statistical confirmed FBG levels (p=0.0008), value 7.69 mmol/L 1.03) 7.24 0.69) intervention. TC also significantly reduced (p=0.016), values 277.96 mg/dL 21.21) 272.19 25.89) Conclusion: FMD might help diseases. Their impact mostly lies effectiveness weight reduction. More research is warranted order fully explore health these diet plans.