Potential Age-Dependent Effects of Estrogen on Neural Injury
نویسندگان
چکیده
منابع مشابه
Neuroprotective Effects of Estrogen Following Neural Injury
Neuroprotective Effects of Estrogen Following Neural Injury Ashley B. Petrone, Carolyn C. Rudy, Taura L. Barr, James W. Simpkins, and Miranda N. Reed Center for Neuroscience, West Virginia University, Morgantown, West Virginia, USA Department of Psychology, West Virginia University, Morgantown, West Virginia, USA School of Nursing, West Virginia University, Morgantown, West Virginia, USA Depart...
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OBJECTIVE 17β-Estradiol (E2) offers cardiovascular protection in young female animals and postmenopausal women. In contrast, randomized trials of menopausal hormones performed in older women have shown harm or no cardiovascular benefit. We hypothesize that E2 effects on vascular inflammation are age dependent. APPROACH AND RESULTS Young (10 weeks) and aged (52 weeks) female C57BL/6 mice were ...
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Renal ischemia–reperfusion; Erythropoietin; Estrogen; Tumor necrosis factor-a; Myeloperoxidase activity; Nitric oxide Abstract Background: Renal ischemia–reperfusion (RIR) is an important etiopathological mechanism of acute renal failure (ARF). Erythropoietin (EPO) has been candidate as a nephroprotectant agent. However, its nephroprotective effect when it is accompanied with estrogen has not b...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2011
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2011.01.057