Potassium-stimulated purine release by cultured sympathetic neurons
نویسندگان
چکیده
منابع مشابه
Potassium-stimulated purine release by cultured sympathetic neurons.
Environmental factors can influence cultured sympathetic neurons to acquire several different neurotransmitter phenotypes. Cholinergic and noradrenergic transmitter status can be influenced by heart cell conditioned medium, chronic depolarization (Patterson, P. H. (1978) Annu. Rev. Neurosci. 1:1-17), and rat serum (Wolinsky, E. J., and P. H. Patterson, (1985) J. Neurosci. 5:1509-1512); formatio...
متن کاملPurine metabolite inosine is an adrenergic neurotrophic substance for cultured chicken sympathetic neurons.
Purines are ubiquitous endogenous cellular metabolites that have been postulated as neurotransmitters or neuromodulators in the nervous system. Recently, we showed that a low-molecular-mass component present in liver-conditioned medium selectively enhances the adrenergic properties of dissociated chicken sympathetic neurons in culture. We report here that this substance is inosine, a purine met...
متن کاملInducing dendritic growth in cultured sympathetic neurons.
The shape of the dendritic arbor determines the total synaptic input a neuron can receive (1-3), and influences the types and distribution of these inputs (4-6). Altered patterns of dendritic growth and plasticity are associated with impaired neurobehavioral function in experimental models (7), and are thought to contribute to clinical symptoms observed in both neurodevelopmental disorders (8-1...
متن کاملElectrically Evoked Release of [3H]Noradrenaline from Mouse Cultured Sympathetic Neurons
Cultured neurons from the thoracolumbar sympathetic chain of newborn mice are known to possess release-inhibiting a2-autoreceptors. The present study was carried out in a search for release-modulating heteroreceptors on these neurons. Primary cultures were preincubated with [H]noradrenaline and then superfused and stimulated by single pulses, trains of 8 pulses at 100 Hz, or trains of 36 pulses...
متن کاملGlycine receptors in cultured chick sympathetic neurons are excitatory and trigger neurotransmitter release.
1. Total RNA isolated from embryonic chick paravertebral sympathetic ganglia was used in a reverse transcription-polymerase chain reaction (RT-PCR) assay with a pair of degenerate oligonucleotide primers deduced from conserved regions of mammalian glycine receptor alpha-subunits. Three classes of cDNA were identified which encode portions of the chicken homologues of the mammalian glycine recep...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1985
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.05-07-01680.1985