Potassium oxonate induces acute hyperuricemia in the tree shrew (<i>tupaia belangeri chinensis</i>)
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منابع مشابه
Potassium oxonate induces acute hyperuricemia in the tree shrew (tupaia belangeri chinensis)
Potassium oxonate, a selectively competitive uricase inhibitor, produced hyperuricemia (HUA) in rodents in a previous study. In this study, we employed the tree shrew as an animal model to study potassium oxonate-induced HUA. The effect of allopurinol (ALLO), a uric acid reducer, was also examined in this model. Potassium oxonate at doses of 5, 20, 40, 60, 80, 100, and 1,000 mg/kg was given int...
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ژورنال
عنوان ژورنال: Experimental Animals
سال: 2017
ISSN: 1341-1357,1881-7122
DOI: 10.1538/expanim.16-0096