Postoperative Vertebral Bone Density Reduction after Pancreaticoduodenectomy for Pancreatic Cancer

Introduction: We can quantitatively estimate vertebral bone density by measuring Hounsfield (HU) units on CT images. Recently, it has been reported that reduction of is associated with postoperative complications and oncologic outcomes. The aim this study to investigate clinical significances after pancreaticoduodenectomy (PD) for pancreas cancer. Methods: retrospectively identified 93 patients who underwent PD pancreatic cancer from January 2000 December 2016. Three mortality cases (3.2%) 7 follow-up loss were excluded, 83 included in study. reviewed the preoperative data, complications, On an axial section at mid-L2-5 level, we obtained mean HU trabecular body. investigated changes index Results: median time was 22 months (range, 3.0 153.0). value 141.2 (± 53.2), 135.6. 52.5). Vertebral statistically age, gender, hypertension, diabetes. In 53 (70.6%), decreased, postoperatively. However, there not significance complication survival outcomes multivariate analysis. Conclusion: measured image decrease patients. study, did derive these changes. Therefore, further investigation large number necessary.