Postoperative CEA is a better prognostic marker than CA19-9, hCGβ or TATI after resection of colorectal liver metastases

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Postoperative CA19-9 Change Is a Useful Predictor of Intrahepatic Cholangiocarcinoma Survival following Liver Resection

BACKGROUND To investigate the clinical significance of the perioperative CA19-9 change for predicting survival in intrahepatic cholangiocarcinoma (ICC) patients treated with surgical resection. METHODS We retrospectively reviewed the data from 74 ICC patients treated with surgical resection between April 2001 and July 2010. Perioperative CA19-9 (preoperative level, postoperative lowest level,...

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Prognostic value of serum tumor antigen CA19-9 after curative resection of colorectal cancer.

BACKGROUND CA19-9 was evaluated as a prognostic marker for colorectal cancer and whether it could be helpful in addition to surveillance using CEA was also tested. MATERIALS AND METHODS Serum CA19-9 levels were measured preoperatively in 1109 patients and monitored at 3-month intervals for the first 2 years postoperatively, and at 6-month intervals thereafter in 700 patients. RESULTS Preope...

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Resection for Colorectal Liver Metastases

Colorectal cancer is the third most frequent cancer in the Western world. About half of the patients develop synchronous or metachronous metastases. The liver is the most common site of such metastases and thus hepatic metastatic disease is a significant socio-medical problem. If it is not treated, the median patient survival is only some months. Surgical resection is the treatment of choice fo...

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Liver resection for colorectal metastases.

PURPOSE More than 50,000 patients in the United States will present each year with liver metastases from colorectal cancers. The current study was performed to determine if liver resection for colorectal metastases is safe and effective and to evaluate predictors of outcome. MATERIALS AND METHODS Data for 456 consecutive resections performed between July 1985 and December 1991 in a tertiary r...

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Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer.

PURPOSE Aberrant activation of epidermal growth factor receptors (EGFR/HER1) by ligand stimulation or heterodimerization with human epidermal growth factor 2 (HER2) is considered to play an important role in the development of colorectal carcinoma. Amphiregulin (AR) is a ligand of EGFR that might be related to the development and progression of gastrointestinal tumors. The aim of this study was...

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ژورنال

عنوان ژورنال: Tumor Biology

سال: 2018

ISSN: 1010-4283,1423-0380

DOI: 10.1177/1010428317752944