Postnatal Changes in Rat Ventricular Function

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Postnatal changes in rat ventricular function.

Experiments were designed to assess the intrinsic changes in myocardial function with age and to determine the role of increasing left ventricular mass in this process. Isometric ventricular pressure-volume curves and length-tension curves were measured in isolated perfused rat hearts of different ages and masses. Incremental tension, peak active tension, and peak passive tension were less for ...

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Postnatal lung function in the developing rat.

Little is known about lung function during early stages of postnatal maturation, although the complex structural changes associated with developing rat lung are well studied. We therefore analyzed corresponding functional (lung volume, respiratory mechanics, intrapulmonary gas mixing, and gas exchange) and structural (alveolar surface area, mean linear intercept length, and alveolar septal thic...

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Postnatal changes in sialylation of glycoproteins in rat liver.

Glycoproteins containing N-linked oligosaccharides were prepared from plasma and liver microsomes of rats aged 0-5 weeks, and galactose and sialic acid content were determined. The sialic acid/galactose ratios in plasma membrane N-glycans remained at about 1 throughout the postnatal period, suggesting that most of the galactose residues are sialylated. In the same way, it was suggested that mos...

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Postnatal changes in dolichol-pathway enzyme activities in rat liver.

The activity of hepatic protein N-glycosylation was compared in rats of different ages by incubating UDP-[14C]glucose with liver microsomes. Dolichyl-phosphate [14C]glucose, [14C]glucosyl-oligosaccharide-lipid and [14C]glycoproteins formed were increased after birth to maximal levels at 2 weeks; thereafter dolichylphosphate [14C]glucose remained constant, while [14C]glucosyl-oligosaccharide-lip...

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Postnatal changes in the developing rat extraocular muscles.

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1973

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.32.6.685