POSTMENOPAUSAL OSTEOPOROSIS: CHRYSIN EXHBITS ESTROGEN-LIKE ACTIVITY IN SILICO
نویسندگان
چکیده
منابع مشابه
In silico analysis of the molecular mechanism of postmenopausal osteoporosis
Postmenopausal osteoporosis (PO) is a common disease in females >50 years of age worldwide and is becoming an increasing burden to society. The present study aimed to assess the molecular mechanism of PO using bioinformatic methods. The gene expression data from patients with PO and normal controls were downloaded from the ArrayExpress database provided by European Bioinformatics Institute. Fol...
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An ongoing need for safe and effective pharmacological therapies exists for postmenopausal osteoporosis, which imposes a significant burden on both women and the health-care system. Bazedoxifene is a novel selective estrogen receptor modulator with a unique tissue-selectivity profile. In phase 3 clinical trials of nearly 10,000 postmenopausal women, bazedoxifene was shown to significantly reduc...
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UNLABELLED Osteoporosis is a systemic disease characterized by low bone mass and alterations in the microstructure of the skeleton. It is a worldwide disease, most prevalent in women over the age of 70. It is estimated that approximately 15-18% of women over 50 years of age are affected by osteoporosis and further 37-50% of women have decreased bone mass. The percentage of men suffering from th...
متن کاملPrimary osteoporosis in postmenopausal women
World Health Organization (WHO) defines natural menopause as at least 12 consecutive months of amenorrhea not due to physiologic and pathologic causes. Statistics show that the mean age of natural menopause is 51 years in industrialized nations, compared to 48 years in poor and non-industrialized nations. With the average life span extended to 70 years, most women will spend more than one third...
متن کاملOsteoporosis in postmenopausal diabetic women; prevalence and related factors
Introduction: Diabetes mellitus and osteoporosis are two frequent medical conditions with an increasing prevalence in elderly. This study is conducted to evaluate osteoporosis in postmenopausal females with type 2 diabetes mellitus in Sanandaj, the provincial center of Kurdistan province in the west of Iran. Methods: From an initial population of 2500 women with ty...
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ژورنال
عنوان ژورنال: Fudma Journal of Sciences
سال: 2023
ISSN: ['2616-1370']
DOI: https://doi.org/10.33003/fjs-2023-0701-1238