Post-Translational Tyrosine Geranylation in Cyanobactin Biosynthesis
نویسندگان
چکیده
منابع مشابه
Recognition Sequences and Substrate Evolution in Cyanobactin Biosynthesis
Ribosomally synthesized and posttranslationally modified peptide (RiPP) natural products are of broad interest because of their intrinsic bioactivities and potential for synthetic biology. The RiPP cyanobactin pathways pat and tru have been experimentally shown to be extremely tolerant of mutations. In nature, the pathways exhibit "substrate evolution", where enzymes remain constant while the s...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2018
ISSN: 0002-7863,1520-5126
DOI: 10.1021/jacs.8b03137