Post‐ ABVD biopsy results, and not post‐ ABVD FDG ‐ PET results, predict outcome in early‐stage Hodgkin lymphoma: response to Adams and Kwee
نویسندگان
چکیده
منابع مشابه
ABVD or BEACOPP for Advanced Hodgkin Lymphoma.
The development of multiagent chemotherapy dramatically changed the prognosis of patients with advanced-stage Hodgkin lymphoma (HL). Although almost all of these patients died when treated with radiotherapy or single-agent chemotherapy, the fourdrug regimen MOPP (mustargen, oncovin, procarbazine, and prednisone) led to remission rates of more than 50% and an overall survival (OS) rate of more t...
متن کاملNeutropenia and Neutropenic Complications in ABVD Chemotherapy for Hodgkin Lymphoma
A combination of Adriamycin (a.k.a. Doxorubicin), Bleomycin, Vinblastine, and Dacarbazine (ABVD) is the most commonly used chemotherapy regime for Hodgkin lymphoma. This highly effective treatment is associated with a significant risk of neutropenia. Various strategies are adopted to counter this commonly encountered problem, including dose modification, use of colony stimulating factors, and p...
متن کامل18F-FDG PET after 2 cycles of ABVD predicts event-free survival in early and advanced Hodgkin lymphoma.
UNLABELLED Our objective was to assess the prognostic value of (18)F-FDG PET after 2 cycles of chemotherapy using doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) in Hodgkin lymphoma (HL) patients overall and in subgroups of patients with early and advanced stages and with low and high risks according to the International Prognostic Score (IPS). METHODS One hundred fifteen patients...
متن کاملPrognostic significance of mid- and post-ABVD PET imaging in Hodgkin's lymphoma: the importance of involved-field radiotherapy.
BACKGROUND Although positron emission tomography (PET) response to chemotherapy (CT) has prognostic significance in Hodgkin's lymphoma (HL), it is unclear whether patients with 2-[fluorine-18]fluoro-2-deoxy-D-glucose (FDG)-PET positivity during and/or after CT can be rendered disease free with consolidative involved-field radiotherapy (IFRT). METHODS Patients with HL treated with adriamycin, ...
متن کاملMicroRNAs as Biomarkers of the Response to Treatment with ABVD Scheme in Hodgkin Lymphoma
Hodgkin Lymphoma (HL) is a neoplasia characterized by the restrict number of malignant cells present in the lymph node. Actual criteria in diagnostic standards don’t consider genetic and epigenetic alterations as risk factors in the development of this disease or in the response of the treatment. MicroRNAs (miRNAs) are important regulatory elements of genic expression that can be altered in the...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2017
ISSN: 0007-1048,1365-2141
DOI: 10.1111/bjh.15072