Possible Relations between Epstein-Barr Virus Past Infection and Classic Multiple Sclerosis in Guilan, Iran
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منابع مشابه
Possible Relations Between Epstein-Barr Virus Past Infection and Classic Multiple Sclerosis in Guilan, Iran
BACKGROUND Multiple sclerosis (MS) is a demyelinating condition affecting the central nervous system. Although the cause of this condition is unknown, patients with MS seem to have genetic vulnerability to certain environmental factors such as infection that could trigger this condition. OBJECTIVES We conducted this study to determine whether MS risk increases following primary infection with...
متن کاملpossible relations between epstein-barr virus past infection and classic multiple sclerosis in guilan, iran
background multiple sclerosis (ms) is a demyelinating condition affecting the central nervous system. although the cause of this condition is unknown, patients with ms seem to have genetic vulnerability to certain environmental factors such as infection that could trigger this condition. objectives we conducted this study to determine whether ms risk increases following primary infection with e...
متن کاملSymptomatic Epstein-Barr virus infection and multiple sclerosis.
In a case-control study of 214 patients with multiple sclerosis, recall of infectious mononucleosis in subjects seropositive for Epstein-Barr viral capsid antigen was associated with a relative risk of 2.9 (95% CI 1.1 to 7.2). Those who reported having infectious mononucleosis before the age of 18 years had a relative risk of multiple sclerosis of 7.9 (95% CI 1.7 to 37.9). The pathogenesis of m...
متن کاملDysregulated Epstein-Barr virus infection in the multiple sclerosis brain
Epstein-Barr virus (EBV), a ubiquitous B-lymphotropic herpesvirus, has been associated with multiple sclerosis (MS), an inflammatory disease of the central nervous system (CNS), but direct proof of its involvement in the disease is still missing. To test the idea that MS might result from perturbed EBV infection in the CNS, we investigated expression of EBV markers in postmortem brain tissue fr...
متن کاملMultiple sclerosis and Epstein-Barr virus.
CONTEXT Infection with Epstein-Barr virus (EBV) has been associated with an increased risk of multiple sclerosis (MS), but the temporal relationship remains unclear. OBJECTIVE To determine whether antibodies to EBV are elevated before the onset of MS. DESIGN, SETTING, AND POPULATION Nested case-control study conducted among more than 3 million US military personnel with blood samples collec...
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ژورنال
عنوان ژورنال: Jundishapur Journal of Microbiology
سال: 2015
ISSN: 2008-3645,2008-4161
DOI: 10.5812/jjm.15985v2