Possible functional role of viral tRNA-like structures
نویسندگان
چکیده
منابع مشابه
Initiation of HIV-1 reverse transcription and functional role of nucleocapsid-mediated tRNA/viral genome interactions.
HIV-1 reverse transcription is initiated from a tRNA(Lys)(3) molecule annealed to the viral RNA at the primer binding site (PBS). The annealing of tRNA(Lys)(3) requires the opening of its three-dimensional structure and RNA rearrangements to form an efficient initiation complex recognized by the reverse transcriptase. This annealing is mediated by the nucleocapsid protein (NC). In this paper, w...
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The surprise was great in the early 1970s when it was shown that valine could be covalently attached to the 3' terminus of the genomic RNA from turnip yellow mosaic virus (TYMV) by valyl-tRNA synthetase (1) and, soon after, that tyrosyland histidyl-tRNA synthetases can aminoacylate the RNAs from brome mosaic virus (BMV) and tobacco mosaic virus (2, 3). The surprise was even greater when it was ...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1984
ISSN: 0014-5793
DOI: 10.1016/0014-5793(84)81183-7