منابع مشابه
Positional information, in bits.
Cells in a developing embryo have no direct way of "measuring" their physical position. Through a variety of processes, however, the expression levels of multiple genes come to be correlated with position, and these expression levels thus form a code for "positional information." We show how to measure this information, in bits, using the gap genes in the Drosophila embryo as an example. Indivi...
متن کاملQualitative Representation of Positional Information
A framework for the qualitative representation of positional information in a two-dimensional space is presented. Qualitative representations use discrete quantity spaces, where a particular distinction is introduced only if it is relevant to the context being modeled. This allows us to build a flexible framework that accommodates various levels of granularity and scales of reasoning. Knowledge...
متن کاملBiological information processing: bits of progress.
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متن کاملPositional information readout in $Ca^{2+}$ signaling
Living cells respond to spatially confined signals. Intracellular signal transmission often involves the release of second messengers like Ca. They will eventually trigger a physiological response, for example, by activating kinases that in turn activate target proteins through phosphorylation. Here, we investigate theoretically how positional information can be accurately read out by protein p...
متن کاملSingle Abrikosov vortices as quantized information bits
Superconducting digital devices can be advantageously used in future supercomputers because they can greatly reduce the dissipation power and increase the speed of operation. Non-volatile quantized states are ideal for the realization of classical Boolean logics. A quantized Abrikosov vortex represents the most compact magnetic object in superconductors, which can be utilized for creation of hi...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2013
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1315642110