POS-774 BORTEZOMIB BASED CHEMOTHERAPY AND BONE MARROW FOLLOWED BY RENAL TRANSPLANTATION IN MULTIPLE MYELOMA: CASE REPORT AND SYSTEMATIC REVIEW
نویسندگان
چکیده
منابع مشابه
Bone marrow transplantation in multiple myeloma: report from the European Cooperative Group for Bone Marrow Transplantation.
Of 14 patients who received an allogeneic bone marrow graft from HLA-compatible sibling donors, 10 have survived for 6 to 34 months posttransplantation (median, 12 months). Four patients have died, two of relapse at extramedullary sites, one of severe acute GVHD, and one from GI bleeding and pericardial effusion. One patient is alive in relapse and four patients have signs of minimal persistent...
متن کاملReversal of acute renal failure by bortezomib-based chemotherapy in patients with multiple myeloma.
Paraprotein induced renal failure is a frequent complication of multiple myeloma and is associated with poor survival. Previously, reversal of renal function has been hampered by the lack of fast acting and highly effective myeloma therapy and most patients remained or became dependent on hemodialysis. Here we show reversal of acute paraprotein-induced renal failure by bortezomib-based therapy ...
متن کاملCase Report on Renal Failure Reversal in Lambda Chain Multiple Myeloma with Bortezomib and Dexamethasone
Renal failure (RF) reversal in multiple myeloma (MM) is associated with an improved prognosis. Light chain myeloma, serum creatinine (SCr) > 4 mg/dL, extensive proteinuria, early infections, and certain renal biopsy findings are associated with lower rates of RF reversal. Our patient is a 67-year-old female with multiple poor prognostic factors for RF reversal who demonstrated a rapid renal res...
متن کاملCost-effectiveness of bortezomib for multiple myeloma: a systematic review.
OBJECTIVES To review published cost-effectiveness analyses (CEA) assessing bortezomib (BTZ) for multiple myeloma (MM) and explore possible bias affecting the cost-effectiveness of BTZ. METHODS Literature was searched for published CEAs assessing BTZ or BTZ-containing regimens for MM from 2003 to 2015. The reported incremental cost-effectiveness ratios (ICER) were adjusted by 2014 country-spec...
متن کاملPyoderma Gangrenosum and Multiple Myeloma: A case report
A 79-year-old female came to skin clinic with an ulcer, 15×20 cm, on her left shin. The laboratory report and both the skin and bone marrow biopsies reports, showed pyoderma gangrenosum associated with multiple myeloma. The patient was referred to hematology clinic for treatment. Multiple myeloma has rarely been associated with pyoderma gangrenosum. Multiple myeloma should be investigated...
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ژورنال
عنوان ژورنال: Kidney International Reports
سال: 2021
ISSN: 2468-0249
DOI: 10.1016/j.ekir.2021.03.806