Portable thermal platform for optimising protein crystallisation
نویسندگان
چکیده
منابع مشابه
The SLS crystallisation platform at beamline X06DA
X-ray crystallography is the most widely used technique for macromolecular structure determination. However, it requires the production of suitable crystals, an iterative and time-consuming process which remains unpredictable. Hence, the rational of the Crystallisation Facility at the Swiss Light Source at the Paul Scherrer Institut was to streamline the steps between intial crystallisation hit...
متن کاملMethods for separating nucleation and growth in protein crystallisation.
The availability of high-quality crystals is crucial to the structure determination of proteins by X-ray diffraction. With the advent of structural genomics the pressure to produce crystals is greater than ever before. Finding favourable conditions for crystallisation is usually achieved by screening of the protein solution with numerous crystallising agents. Optimisation of the crystallisation...
متن کاملNearly-Deterministic Methods for Optimising Protein Geometry
c © 2008 by John von Neumann Institute for Computing Permission to make digital or hard copies of portions of this work for personal or classroom use is granted provided that the copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. To copy otherwise requires prior specific permission by the publisher ment...
متن کاملSimple models for charge and salt effects in protein crystallisation
A simple extension of existing models for protein crystallisation is described, in which salt ions and charge neutrality are explicitly incorporated. This provides a straightforward explanation for the shape of protein crystallisation boundaries, the associated scaling properties seen for lysozyme, and can also explain much of the salt dependence of the second virial coefficient. The analysis h...
متن کاملProtein considerations for optimising skeletal muscle
Skeletal muscle is critical for human health. Protein feeding, alongside resistance exercise, 12 is a potent stimulus for muscle protein synthesis (MPS) and is a key factor that regulates skeletal 13 muscle mass (SMM). The main purpose of this narrative review was to evaluate the latest evidence 14 for optimising the amino acid or protein source, dose, timing, pattern and macronutrient coingest...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 2008
ISSN: 0108-7673
DOI: 10.1107/s0108767308081373