Pore properties of Lymnaea stagnalis neuron stretch-activated K+ channels

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Modelling a Respiratory Central Pattern Generator Neuron in Lymnaea Stagnalis

Lymnaea stagnalis, often termed the great pond snail, is characterized in part by its ability to take in oxygen both cutaneously and aerially (via its rudimentary lung). The central nervous system of the Lymnaea is composed of a relatively small number of large, identifiable neurons. In 1990, Syed et al. [1] established that respiratory rhythmogenesis in the Lymnaea is controlled by a 3-neuron ...

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Dynamic properties of stretch-activated K+ channels in adult rat atrial myocytes.

The effect of mechanical stress on the heart's electrical activity has been termed mechanoelectric feedback. The response to stretch depends upon the magnitude and the waveform of the stimulus, and upon the timing relative to the cardiac cycle. Stretch-activated ion channels (SACs) have been regarded as the most likely candidates for serving as the primary transducers of mechanical stress. We e...

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Predator detection in Lymnaea stagnalis.

Laboratory-reared Lymnaea are capable of detecting and responding to the scent of a crayfish predator. The present investigation is a first attempt to characterize multiple stress-related behavioural responses resulting from predator detection and to depict the neurophysiological correlates of one of these illustrated behaviours. Snails respond to crayfish effluent (CE) by increasing the follow...

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Potassium channels in primary cultures of seawater fish gill cells. I. Stretch-activated K(+) channels.

Previous studies using the patch-clamp technique demonstrated the presence of a small conductance Cl(-) channel in the apical membrane of respiratory gill cells in primary culture originating from sea bass Dicentrarchus labrax. We used the same technique here to characterize potassium channels in this model. A K(+) channel of 123 +/- 3 pS was identified in the cell-attached configuration with 1...

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Expression of Stretch-Activated Two-Pore Potassium Channels in Human Myometrium in Pregnancy and Labor

BACKGROUND We tested the hypothesis that the stretch-activated, four-transmembrane domain, two pore potassium channels (K2P), TREK-1 and TRAAK are gestationally-regulated in human myometrium and contribute to uterine relaxation during pregnancy until labor. METHODOLOGY We determined the gene and protein expression of K2P channels in non-pregnant, pregnant term and preterm laboring myometrium....

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ژورنال

عنوان ژورنال: Journal of Experimental Biology

سال: 1995

ISSN: 1477-9145,0022-0949

DOI: 10.1242/jeb.198.9.1919