Population pharmacokinetics of ticarcillin in critically ill patients receiving extended daily diafiltration
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چکیده
منابع مشابه
Using population pharmacokinetics to dose gentamicin 1 during extended - daily diafiltration in critically ill patients with 2 acute kidney injury
28 The objective of this prospective pharmacokinetic study was to describe the variability of 29 gentamicin plasma concentrations in critically ill patients with AKI necessitating extended30 daily-diafiltration (EDD-f) using a population pharmacokinetic model and to subsequently 31 perform Monte Carlo dosing simulations to determine which dose regimen achieves 32 pharmacodynamic targets most co...
متن کاملUsing population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury.
The objective of the present prospective pharmacokinetic study was to describe the variability of plasma gentamicin concentrations in critically ill patients with acute kidney injury (AKI) necessitating extended daily diafiltration (EDD-f) using a population pharmacokinetic model and to subsequently perform Monte Carlo dosing simulations to determine which dose regimen achieves the pharmacodyna...
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BACKGROUND AND OBJECTIVES Although the pharmacokinetics of dexmedetomidine in healthy volunteers have been studied, there are limited data about the pharmacokinetics of long-term administration of dexmedetomidine in critically ill patients. METHODS This population pharmacokinetic analysis was performed to quantify the pharmacokinetics of dexmedetomidine in critically ill patients following in...
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The pharmacokinetic parameters of amikacin were determined in a population of 20 adults and 36 pediatric patients admitted into an intensive care unit. Amikacin was administered by repeated intravenous infusion over 0.5 h (600 to 1,350 mg for adults; 70 to 1,500 mg for children). The number of administrations ranged from 2 to 17, and the number of samples collected from each patient ranged from...
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There is no randomized study carried out in order to compare their pharmacokinetic parameters although midazolam, as a sedative, has been widely administered via continuous infusion as well as intermittent bolus doses in mechanically ventilated critically ill patients. We prospectively investigated the effect of these two principal methods on pharmacokinetic parameters in 23 of mentioned patien...
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ژورنال
عنوان ژورنال: International Journal of Antimicrobial Agents
سال: 2019
ISSN: 0924-8579
DOI: 10.1016/j.ijantimicag.2019.06.027