Population Dynamics of the East African Sleeping Sickness

East African sleeping sickness in Chennai.

A traveler to East Africa developed fever, an eschar on his forearm and thrombocytopenia shortly after returning home to Chennai, India. Trypanosoma brucei rhodesiense infection was diagnosed on examination of his peripheral smear. He made a full recovery after receiving a course of suramin.

Sleeping sickness – human African trypanosomiasis

some new leads for human african trypanosomiasis (african sleeping sickness)

History of sleeping sickness in East Africa.

The history of human sleeping sickness in East Africa is characterized by the appearance of disease epidemics interspersed by long periods of endemicity. Despite the presence of the tsetse fly in large areas of East Africa, these epidemics tend to occur multiply in specific regions or foci rather than spreading over vast areas. Many theories have been proposed to explain this phenomenon, but re...

Molecular epidemiology of African sleeping sickness.

Human sleeping sickness in Africa, caused by Trypanosoma brucei spp. raises a number of questions. Despite the widespread distribution of the tsetse vectors and animal trypanosomiasis, human disease is only found in discrete foci which periodically give rise to epidemics followed by periods of endemicity A key to unravelling this puzzle is a detailed knowledge of the aetiological agents respons...