Population-based microbial computing: a third wave of synthetic biology?
نویسندگان
چکیده
منابع مشابه
Population-based microbial computing: a third wave of synthetic biology?
Synthetic biology is an emerging research field, in which engineering principles are applied to natural, living systems. A major goal of synthetic biology is to harness the inherent “biological nanotechnology” of living cells for the purposes of computation, production, or diagnosis. As the field evolves, it is gradually developing from a singlecell approach (akin to using standalone computers)...
متن کاملEcological perspectives on synthetic biology: insights from microbial population biology
The metabolic capabilities of microbes are the basis for many major biotechnological advances, exploiting microbial diversity by selection or engineering of single strains. However, there are limits to the advances that can be achieved with single strains, and attention has turned toward the metabolic potential of consortia and the field of synthetic ecology. The main challenge for the syntheti...
متن کاملSYNTHETIC BIOLOGY. Emergent genetic oscillations in a synthetic microbial consortium.
A challenge of synthetic biology is the creation of cooperative microbial systems that exhibit population-level behaviors. Such systems use cellular signaling mechanisms to regulate gene expression across multiple cell types. We describe the construction of a synthetic microbial consortium consisting of two distinct cell types—an "activator" strain and a "repressor" strain. These strains produc...
متن کاملAdvancing bacteriophage-based microbial diagnostics with synthetic biology.
Figure 1. Engineered bacteriophages can be assembled into sensitive, specific, and rapid microbial diagnostics. (A) Bacteriophages can be designed to express reporter payloads during specific microbial infection, leading to the production of detectable outputs. (B) Designing synthetic bacteriophages as microbial Synthetic biology is an emerging engineering field focused on designing artificial ...
متن کاملApplications of Synthetic Biology in Microbial Biotechnology
1Department of Chemical Engineering, The University of Texas at Austin, 1 University Station, C0400, Austin, TX 78712, USA 2Department of Chemical Engineering, The Pennsylvania State University, 226A Fenske Laboratory, University Park, PA 16802-4400, USA 3Department of Chemical and Biomolecular Engineering, University of Maryland, 1208D, Chemical and Nuclear Engineering Building 090, College Pa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of General Systems
سال: 2014
ISSN: 0308-1079,1563-5104
DOI: 10.1080/03081079.2014.921001