منابع مشابه
Glucocorticoids induce retinal toxicity through mechanisms mainly associated with paraptosis.
PURPOSE Corticosteroids have recorded beneficial clinical effects and are widely used in medicine. In ophthalmology, besides their treatment benefits, side effects, including ocular toxicity have been observed especially when intraocular delivery is used. The mechanism of these toxic events remains, however, poorly understood. In our present study, we investigated the mechanisms and potential p...
متن کامل[Retinal toxicity following chloroquine therapy].
CASE REPORT Two cases of bilateral ocular toxicity following chloroquine therapy in two women with systemic lupus erythematosus are presented. DISCUSSION Retinal toxicity due to chloroquine is an uncommon iatrogenic disease. It is dose-dependent. New cases are still being described despite the application of ophthalmic screening techniques.
متن کاملPoppers: legal highs with questionable contents? A case series of poppers maculopathy.
BACKGROUND Poppers are volatile alkyl nitrite compounds that are inhaled to enhance sexual experience and for their psychoactive effects. A less well-known side effect is foveal maculopathy, which has emerged following changes in their chemical composition. It is unclear if certain individuals are more susceptible to retinal damage or if there is a relationship between pattern of inhalation and...
متن کاملPoppers Compound Risk for Hiv Infection
Dax EM, et al. “Amyl nitrite alters human in vitro immune function.” Immunopharmacology and Immunotoxicity 1991;13(4):557-587. PMID: 1685501. “The changes in lymphocyte function observed in this study suggest that volatile nitrite inhalation results in a cycle of modest immunosuppression followed by gradual recovery after cessation of drug. NK (natural killer) activity was most noticeably effec...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2010
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmc1005118