منابع مشابه
EphB1 is underexpressed in poorly differentiated colorectal cancers.
BACKGROUND Over- or underexpression of certain Eph receptors has been associated with tumorigenesis of some types of cancer. EphB1 is a member of receptor tyrosine kinases of the EphB subfamily involved in the development, progress and prognosis of colorectal cancers. The expression levels of EphB1 in colon cancer cell lines and human colorectal carcinoma specimens were determined and associati...
متن کاملpoorly-differentiated bronchial carcinoma
The production of serotonin (5-hydroxtryptamine) and certain related metabolites by tumours associated with the clinical carcinoid syndrome has now been well established. Many of the reported cases have concerned carcinoid tumours of the intestinal tract (Thorson, 1958 ; Macfarlane, Dalgliesh, Dutton, Lennox, Nyhus, and Smith, 1956) but tumours histologically resembling carcinoids, and also app...
متن کاملA cell surface glycoprotein expressed by colorectal carcinomas including poorly differentiated, noncarcinoembryonic antigen-producing colorectal tumors.
A monoclonal antibody to a cell surface glycoprotein on human colorectal carcinomas was raised using the undifferentiated colon carcinoma cell line MIP 101 as the immunogen. This antibody, ND4, is an IgG2a which does not cross-react with carcinoembryonic antigen (CEA), non-specific cross-reacting antigen, or blood group substances A, B, and H. Immunoprecipitation using lysates of cells grown in...
متن کاملGenomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers.
BACKGROUND Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) are rare and frequently lethal tumors that so far have not been subjected to comprehensive genetic characterization. METHODS We performed next-generation sequencing of 341 cancer genes from 117 patient-derived PDTCs and ATCs and analyzed the transcriptome of a representative subset of 37 tumors. Results...
متن کاملNeuroendocrine Differentiation Is a Prognostic Factor for Stage II Poorly Differentiated Colorectal Cancer
Neuroendocrine differentiation (NED) in colorectal cancer is an indistinct phenomenon and may define a new cancer subtype, especially in the poorly differentiated colorectal cancer (PDCRC). The clinical features of PDCRC with NED remain controversial, thus confusing the implementation of individualized treatment. This study included 171 patients who underwent surgery from 2000 to 2011 and had p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2013
ISSN: 1943-7722,0002-9173
DOI: 10.1309/ajcp8p2dynkgrbvi