Poor response to oral indomethacin therapy for persistent ductus arteriosus in very low birthweight infants.
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چکیده
منابع مشابه
Poor response to oral indomethacin therapy for persistent ductus arteriosus in very low birthweight infants.
Administration of oral indomethacin to treat cardiorespiratory failure in 7 low birthweight infants, after failure of conventional therapy, produced an improvement in only 2 infants. These infants had a higher birthweight than the group as a whole. Surgical ligation, rather than oral indomethacin, may be the treatment of choice for persistent ductus arteriosus in very low birthweight infants.
متن کاملIndomethacin treatment for patent ductus arteriosus in very low birthweight infants: double blind trial.
Thirty very low birthweight (VLBW) infants (mean gestational age 28.9 weeks; mean birthweight 1138 g) with symptomatic patent ductus arteriosus (PDA) were entered in a randomised double blind trial of indomethacin treatment. The mean age at diagnosis was 7.6 days and at entry to the trial 10.7 days. Before treatment for PDA the indomethacin and placebo groups were well matched for gestational a...
متن کاملProlonged low dose indomethacin for persistent ductus arteriosus of prematurity.
A total of 121 infants who required indomethacin for persistent ductus arteriosus in Liverpool and Cambridge over a four year period were randomised to receive either 0.1 mg/kg daily for six days or 0.2 mg/kg every 12 hours for three doses. The groups were of similar birth weight and gestational and postnatal age, though those treated with a low dose were by chance receiving a higher percentage...
متن کاملOral ibuprofen versus intravenous indomethacin for closure of patent ductus arteriosus in very low birth weight infants.
BACKGROUND The purpose of this study is to compare the effects and complications of pharmacologic closure of patent ductus arteriosus (PDA) by intravenous indomethacin or oral ibuprofen in neonates weighing <1500 g at birth [very low birth weight (VLBW) infants]. METHODS This is a retrospective study of infants treated with intravenous indomethacin (0.2 mg/kg initially followed by two doses a...
متن کاملFailure of indomethacin to close persistent ductus arteriosus in infants weighing under 1000 grams.
Six preterm infants with a persistent ductus arteriosus, who failed to improve with conventional medical management, received indomethacin in an attempt to close the duct pharmacologically. All infants weighed less than 1000 g when the drug was administered. All showed a transient response to indomethacin; however, no infant demonstrated a permanent response, even though 5 of the 6 received mul...
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ژورنال
عنوان ژورنال: Heart
سال: 1979
ISSN: 1355-6037
DOI: 10.1136/hrt.41.3.301