Pooling biospecimens and limits of detection: effects on ROC curve analysis
نویسندگان
چکیده
منابع مشابه
Pooling biospecimens and limits of detection: effects on ROC curve analysis.
Frequently, epidemiological studies deal with two restrictions in the evaluation of biomarkers: cost and instrument sensitivity. Costs can hamper the evaluation of the effectiveness of new biomarkers. In addition, many assays are affected by a limit of detection (LOD), depending on the instrument sensitivity. Two common strategies used to cut costs include taking a random sample of the availabl...
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ROC Curve
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2006
ISSN: 1465-4644,1468-4357
DOI: 10.1093/biostatistics/kxj027