POLYURIA (DIABETES INSIPIDUS) IN BASAL CEREBRAL DISEASE
نویسندگان
چکیده
منابع مشابه
Polyuria with the Concurrent manifestation of Central Diabetes Insipidus (CDI) & Type 2 Diabetes Mellitus (DM)
We report a rare case of the concurrent manifestation of central diabetes insipidus (CDI) and type 2 diabetes mellitus (DM). A 56 year-old man was diagnosed as a type 2 DM on the basis of hyperglycemia with polyuria and polydipsia at a local clinic two months ago and started an oral hypoglycemic medication, but resulted in no symptomatic improvement at all. Upon admission to the university hosp...
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A 17-year-old girl presented with polyuria (7 L/day) and polydipsia for one year. Initial urine osmolality was 113mOsm/kg H2O. Following 6 h of fluid restriction, serum plasma osmolality reached 300mOsm/kg H2O, whereas urine osmolality was 108mOsm/kg H2O. Urine osmolality was increased by 427% from 108 to 557mOsm/kg after vasopressin challenge. The patient was diagnosed with central diabetes in...
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Familial neurohypophysial diabetes insipidus (FNDI), an autosomal dominant disorder, is mostly caused by mutations in the gene of neurophysin II (NPII), the carrier protein of arginine vasopressin (AVP). Previous studies suggest that loss of AVP neurons might be the cause of polyuria in FNDI. Here we analyzed knockin mice expressing mutant NPII that causes FNDI in humans. The heterozygous mice ...
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A 45-year-old man was hospitalized because of weight loss, finger tremor, thirst, polydipsia and increased urinary frequency. He was diagnosed with Graves' disease (GD) and central diabetes insipidus (CDI). Magnetic resonance imaging revealed the enlarged posterior pituitary with thickened stalk. Histological examination obtained from biopsy of the pituitary revealed lymphocytic infundibulo-neu...
متن کاملPolyuria due to central diabetes insipidus presenting as an early manifestation of acute myeloid leukemia.
Diabetes insipidus is a polyuric syndrome characterized by a pathologic excretion of large amounts of urine with low osmolality. It can originate from a total or partial lack of antidiuretic hormone (ADH) production from the pituitary gland or from “resistance” of the collecting tubules of the kidney to the ADH. Acute monocytic leukemia infiltrates the central nervous system in up to 50% of cas...
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ژورنال
عنوان ژورنال: Brain
سال: 1893
ISSN: 0006-8950,1460-2156
DOI: 10.1093/brain/16.3.440