Polymyxins: a new hope in combating Gram-negative superbugs?
نویسندگان
چکیده
منابع مشابه
Teaching ‘Old’ Polymyxins New Tricks: New-Generation Lipopeptides Targeting Gram-Negative ‘Superbugs’
The antimicrobial lipopeptides polymyxin B and E (colistin) are being used as a 'last-line' therapy for infections caused by multidrug-resistant Gram-negative pathogens. Polymyxin resistance implies a total lack of antibiotics for the treatment of life-threatening infections caused by the Gram-negative 'superbugs'. This report details the structure-activity relationships (SAR) based design, in ...
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ژورنال
عنوان ژورنال: Future Medicinal Chemistry
سال: 2016
ISSN: 1756-8919,1756-8927
DOI: 10.4155/fmc-2016-0091