Polymorphic gene tlr2 markers in latent syphilis and seroresistance

UGT1A1 gene linkage analysis: application of polymorphic markers rs4148326/rs4124874 in the Iranian population

Objective(s): Mutations in the UGT1A1 gene are responsible for hyperbilirubinemia syndromes including Crigler-Najjar type 1 and 2 and Gilbert syndrome. In view of the genetic heterogeneity and involvement of large numbers of the disease causing mutations, the application of polymorphic markers in the UGTA1 gene could be useful in molecular diagnosis of the disease. Materials and Methods: In the...

Latent Syphilis in the Tropics

Case 2.?S. M? a Bengalee Hinduwas som i-Was admitted for attacks of _rm}ttent. On r'x!!rf -s rmittent and sometime3 found to lio inatlon fl1R l>ver and the spleei ... (though bc enlarged and the aldehyde test was positive ^ not strongly positive). This seemed to be a case of kala-azar?but on sternum puncture and also on liver puncture and culture no leishmania was found. On / enquiry it was fou...

Heterozygosis deficit of polymorphic markers linked to the β-globin gene cluster region in the Iranian population

Objective(s): Iran is considered as one of the high-prevalence areas for β-thalassemia with a rate of about 10% carrier frequency. Molecular diagnosis of the disease is performed both by direct sequencing and indirectly by the use of polymorphic markers present in the beta globin gene cluster. However, to date there is no reliable information on the application of the markers in the Iranian pop...

Latent Syphilis and the Autonomic Nervous System

Tests of Cure in Treated Early and Latent Syphilis.

To show accurately and statistically the end results of therapy of a large number of cases of syphilis treated with penicillin is unfortunately hardly possible in Great Britain, where a patient is free to come and go as he wishes, because of the natural tendency to default from long observation. The best that can be done is to collect and evaluate one's experiences after following for many year...