Polymerization and Copolymerization of 2-Methyl-and 2-Phenyl-N-Vinyl Imidazole
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Design and Synthesis of 2-Methyl and 2-Methyl-4-Nitro Imidazole Derivatives as Antifungal Agents
Two series (a and b) of N- substituted heteroaromatic compounds related to clotrimazole were synthesized. Imidazole ring of the clotrimazole was replaced by 2-methylimidazole in series a, and by 2-methyl-4-nitroimidazole in series b. O-cholortrityl moiety of clotrimazole was also replaced by trityl, mono or dimethoxy trityl. Chemical structures...
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In the title compound, C(9)H(8)N(2), a mirror plane lies perpendicular to the phenyl and imidazole rings and passes through the bridging C-C bond, so that the imidazole ring is disordered over two sites about the mirror plane with the equal site occupancy; the asymmetric unit contains one half-mol-ecule. In the crystal, adjacent mol-ecules are linked via N-H⋯N hydrogen bonds.
متن کاملdesign and synthesis of 2-methyl and 2-methyl-4-nitro imidazole derivatives as antifungal agents
two series (a and b) of n- substituted heteroaromatic compounds related to clotrimazole were synthesized. imidazole ring of the clotrimazole was replaced by 2-methylimidazole in series a, and by 2-methyl-4-nitroimidazole in series b. o-cholortrityl moiety of clotrimazole was also replaced by trityl, mono or dimethoxy trityl. chemical structures of all the new compounds were confirmed by spec-tr...
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In the title compound, C(18)H(16)N(2)O(2)·H(2)O, the dihedral angle between the quinoline ring system and the benzene ring is 87.19 (8)°. In the crystal, water mol-ecules are linked to acetamide mol-ecules via inter-molecular O-H⋯N and O-H⋯O hydrogen bonds.
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ژورنال
عنوان ژورنال: Kobunshi Kagaku
سال: 1964
ISSN: 1884-8079,0023-2556
DOI: 10.1295/koron1944.21.625