Polymer Substrate with Surface Solvent Reservoir for Polymer-Spray Mass Spectrometric Analysis of Hydrophilic Drugs

Effect of polymer surface modification on polymer-protein interaction via hydrophilic polymer grafting.

Surface modification of flat sheet ultrafiltration membranes, polyethersulfone (PES), was investigated to improve the hydrophilicity of the membrane surface thereby reducing adsorption of the proteins onto the membrane. Grafting of hydrophilic polymers onto UV/ozone-treated PES was used to improve the hydrophilicity of the commercial PES membranes. Hydrophilic polymers, that is, poly(vinyl alco...

Application of Interferometry to Analysis of Polymer-Polymer and Polymer-Solvent Interactions

For prediction of polymer systems behavior on processing and exploiting stages knowledge of phase diagrams is very useful and in some cases – necessary. They characterize equilibrium phase states and for particular systems – phase structure. Among other methods to estimate compatibility of two substances including polymeric one, and consequently to obtain reasonable information about phase stat...

Mechanical properties of a hydrophilic acrylic polymer.

Acrylic polymers with hydrophilic groups (i.e., ethyl hydroxyl) may be prepared that convert to a soft elastic gel by absorbing water. Such a polymer has been applied t o dentistry for use as an elastic lining material for dentures. A commercial product, Hydron, was used in this study. The linear expansion of this material after 520 hr of water immersion was found to be 20.4%. Hardness was foun...

Influence of solvent/polymer interaction on miscibility of PMMA/PCL blend: thermal analysis approach

Top-down mass spectrometry of hybrid materials with hydrophobic peptide and hydrophilic or hydrophobic polymer blocks.

A multidimensional mass spectrometry (MS) methodology is introduced for the molecular level characterization of polymer-peptide (or polymer-protein) copolymers that cannot be crystallized or chromatographically purified. It encompasses electrospray ionization (ESI) or matrix-assisted laser desorption ionization (MALDI) coupled with mass analysis, tandem mass spectrometry (MS(2)) and gas-phase s...