Polymer Brushes as Functional, Patterned Surfaces for Nanobiotechnology

Y-Shaped Polymer Brushes: Nanoscale Switchable Surfaces

We report a first observation of nanoscale surface structures of segregated pinned micelles of grafted Y-shaped molecules and their reversible structural reorganization. We designed a novel type of Y-shaped molecules combining two highly incompatible polymer chains (arms) attached to a single focal point capable of chemical grafting to a functionalized silicon surface. We demonstrated that spat...

Polymer brushes on periodically nanopatterned surfaces.

Structural properties of polymer brushes tethered on a periodically nanopatterned substrate are investigated by computer simulations. The substrate consists of an alternating succession of two different types of equal-width parallel stripes, and the polymers are end-tethered selectively on every second stripe. Three distinct morphologies of the nanopatterned brush have been identified, and thei...

Discriminatory Bio-Adhesion Over Nano-Patterned Polymer Brushes

Patterned Biofunctional Polymer Brushes CNF Project # 640 - 97 Principal Investigator :

Protein patterning was carried out using a simple procedure based on photolithography wherein the protein was not subjected to UV irradiation and high temperatures, or contacted with denaturing solvents, and strongly acidic or basic solutions. Self-assembled monolayers of poly(ethylene glycol) (PEG) on silicon surfaces were exposed to oxygen plasma through a patterned photoresist. The etched re...

Patterned biofunctional poly(acrylic acid) brushes on silicon surfaces.

Protein patterning was carried out using a simple procedure based on photolithography wherein the protein was not subjected to UV irradiation and high temperatures or contacted with denaturing solvents or strongly acidic or basic solutions. Self-assembled monolayers of poly(ethylene glycol) (PEG) on silicon surfaces were exposed to oxygen plasma through a patterned photoresist. The etched regio...