Poly(lactic-co-glycolic acid) microspheres as a potential bulking agent for urological injection therapy: Preliminary results
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چکیده
منابع مشابه
Application of a novel approach to prepare biodegradable polylactic-co-glycolic acid microspheres: surface liquid spraying.
A novel approach which had foreground of industrialization, surface liquid spraying, was studied in this paper to prepare biodegradable polylactic-co-glycolic acid (PLGA) microspheres for controlled release drug delivery system. To compare with the normal methods, the microspheres prepared by this approach were characterized by particle size distribution and photograph of microscope. The relati...
متن کاملProtective effect of recombinant staphylococcal enterotoxin A entrapped in polylactic-co-glycolic acid microspheres against Staphylococcus aureus infection
Staphylococcus aureus is an important cause of nosocomial and community-acquired infections in humans and animals, as well as the cause of mastitis in dairy cattle. Vaccines aimed at preventing S. aureus infection in bovine mastitis have been studied for many years, but have so far been unsuccessful due to the complexity of the bacteria, and the lack of suitable vaccine delivery vehicles. The c...
متن کاملPractical preparation procedures for docetaxel-loaded nanoparticles using polylactic acid-co-glycolic acid
BACKGROUND Nanoparticles fabricated from the biodegradable and biocompatible polymer, polylactic-co-glycolic acid (PLGA), are the most intensively investigated polymers for drug delivery systems. The objective of this study was to explore fully the development of a PLGA nanoparticle drug delivery system for alternative preparation of a commercial formulation. In our nanoparticle fabrication, ou...
متن کاملLoading of Gentamicin Sulfate into Poly (Lactic-Co-Glycolic Acid) Biodegradable Microspheres
Objective: In dental treatments, use of carriers for targeted antibiotic delivery would be optimal to efficiently decrease microbial count. In this study, gentamicin was loaded into polylactic co-glycolic acid (PLGA) microspheres and its release pattern was evaluated for 20 days. Methods: In this experimental study, PLGA microspheres loaded with gentamycin were produced by the W/O/W method....
متن کاملSafety evaluation of poly(lactic-co-glycolic acid)/poly(lactic-acid) microspheres through intravitreal injection in rabbits
Poly(lactic-co-glycolic acid) (PLGA) and/or poly(lactic-acid) (PLA) microspheres are important drug delivery systems. This study investigated eye biocompatibility and safety of PLGA/PLA microspheres through intravitreal injection in rabbits. Normal New Zealand rabbits were randomly selected and received intravitreal administration of different doses (low, medium, or high) of PLGA/PLA microspher...
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ژورنال
عنوان ژورنال: Journal of Biomedical Materials Research
سال: 2004
ISSN: 0021-9304,1097-4636
DOI: 10.1002/jbm.b.30138