Polyclonal response of human lymphocytes to Chlamydia trachomatis

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Polyclonal response of human lymphocytes to Chlamydia trachomatis.

The mitogenicity of Chlamydia trachomatis was investigated. Umbilical cord blood cells from healthy newborns were used. These cells were stimulated in cultures with partially purified C. trachomatis elementary bodies. Proliferation of cultured lymphocytes and secreted immunoglobulins and leukocyte migration inhibitory factor were measured in the culture supernatants. Our results showed that C. ...

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In this issue of the Journal, Geisler and colleagues [1] report convincing epidemiological evidence that cervical infection with Chlamydia trachomatis produces immunity in at least a subset of naturally infected women. Over a 2.5-year period, they enrolled 243 C. trachomatis–infected women in a treatment study. A standardized nucleic acid amplification test with high predictive value was used t...

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Immuno-gold Labelling of Chlamydia trachomatis

Background Chlamydia trachomatis is considered as an important cause of preventable sexually transmitted diseases worldwide. It is known to be of an obligate intracellular nature and enters its target cells via an endocytic process. As major outer membrane protein (MOMP) is one of the main candidates for the attachment and entry of chlamydia to the host cells we have tried to label the epitopes...

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Anti-Chlamydia trachomatis antibodies and abortion in women referring to

Introduction: Fetal loss and abortion are responsible for significant emotional distress for couples desiring children. Regarding the etiologic importance, this study has been carried out to determine the prevalence of Anti-Chlamydia trachomatis antibodies in normal women and women with abortion. Methods: In this descriptive study 120 women with definite diagnosis of abortion as patients and ...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1986

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.54.1.28-31.1986