Point: Visceral Adiposity Is Causally Related to Insulin Resistance

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Point: visceral adiposity is causally related to insulin resistance.

Related to Insulin Resistance The relationship between obesity and insulin resistance, while well recognized for many years, has nonetheless been confusing since not all obese individuals have insulin resistance (1) and because insulin resistance occurs in individuals who have BMIs that are within the normal or mildly overweight categories (2). Early attempts to understand the relationships bet...

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Counterpoint: visceral adiposity is not causally related to insulin resistance.

Causally Related to Insulin Resistance I t has been known for over half a century that accumulation of fat in the upper body is associated with metabolic complications of obesity. The mechanism responsible for this association is widely believed to be insulin resistance, which is frequently present in individuals with upper-body obesity (1) and is associated with increased cardiovascular risk (...

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Visceral adiposity, insulin resistance and cancer risk

BACKGROUND There is a well established link between obesity and cancer. Emerging research is characterising this relationship further and delineating the specific role of excess visceral adiposity, as opposed to simple obesity, in promoting tumorigenesis. This review summarises the evidence from an epidemiological and pathophysiological perspective. METHODS Relevant medical literature was ide...

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Title Contribution of visceral adiposity and insulin resistance to metabolic

We investigated the relative impacts of visceral adiposity and insulin resistance on the metabolic risk profile in middle-aged Japanese men. A cross-sectional study was conducted in 636 nondiabetic Japanese men with a mean age of 51.6 years. Visceral adipose tissue (AT) was assessed using computed tomography and insulin resistance was determined by the homeostasis model assessment insulin resis...

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Exenatide with Metformin Ameliorated Visceral Adiposity and Insulin Resistance

Background To study the effectiveness of exenatide with metformin and sequential treatment with exenatide and glargine added to metformin and their influence on insulin sensitivity and adipose distribution. Methods 20 newly diagnosed obese type 2 diabetic patients were enrolled, and 2-month washout treatment of metformin, 6-month exenatide treatment, and 6-month glargine treatment were admini...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2005

ISSN: 0149-5992,1935-5548

DOI: 10.2337/diacare.28.9.2322