Podophyllotoxin Content and Yield of American Mayapple Leaves in Sun and Shade
نویسندگان
چکیده
منابع مشابه
Post-harvest and scale-up extraction of American mayapple leaves for podophyllotoxin production
Leaves of American mayapple (Podophyllum peltatum L.) are of interest to the pharmaceutical industry as an alternative source of podophyllotoxin, an aryltetralin lignan that is the precursor of widely used anticancer drugs etoposide, teniposide, and etopophos. In this study, the effects of post-harvest handling were evaluated by inflicting physical damage to leaves of mayapple to simulate rough...
متن کاملThe American Mayapple and its Potential for Podophyllotoxin Production*
INTRODUCTION Podophyllotoxin is the starting material for the semi-synthesis of the anti-cancer drugs etoposide, teniposide and etopophos. These compounds have been used for the treatment of lung and testicular cancers as well as certain leukemias. It is also the precursor to a new derivative CPH 82 that is being tested for rheumatoid arthritis in Europe, and it is the precursor to other deriva...
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Podophyllotoxin Content in Leaves of Eastern Red Cedar (Juniperus virginiana)
Eastern red cedar (Juniperus virginiana L. Cupressaceae) occurs naturally throughout eastern North America and has been identified as a source of podophyllotoxin. Podophyllotoxin is used to manufacture drugs for treatment of cancer, rheumatoid arthritis, genital warts, psoriasis, and multiple sclerosis. Leaf material was collected from Juniperus plants located in northern Mississippi once a mon...
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ژورنال
عنوان ژورنال: HortScience
سال: 2005
ISSN: 0018-5345,2327-9834
DOI: 10.21273/hortsci.40.1.60